Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215939 | 1.00 | CNKSR1 (0.44) | CNKSR1CYP3A4TTRDPP4CA12 | |
| Hydrochloric Acid SCHEMBL11214275 | 0.99 | CNKSR1 (0.44) | CNKSR1CYP3A4TTRDPP4CA12 | |
| Hydrochloric Acid SCHEMBL11214276 | 0.99 | CNKSR1 (0.44) | CNKSR1CYP3A4TTRDPP4CA12 | |
| SCHEMBL11216858 | 0.91 | CYP3A4 (0.50) | CNKSR1CYP3A4TTRDPP4CA12 | |
| SCHEMBL11216857 | 0.91 | CYP3A4 (0.50) | CNKSR1CYP3A4TTRDPP4CA12 | |
| Hydrochloric Acid SCHEMBL11215040 | 0.90 | CNKSR1 (0.49) | CNKSR1CYP3A4TTRDPP4CA12 | |
| Hydrochloric Acid SCHEMBL11215035 | 0.90 | CNKSR1 (0.49) | CNKSR1CYP3A4TTRDPP4CA12 | |
| SCHEMBL11218534 | 0.85 | ALDH1A1 (0.38) | TTRCA12CA1CA2CA7 | |
| SCHEMBL11218536 | 0.85 | ALDH1A1 (0.38) | TTRCA12CA1CA2CA7 | |
| SCHEMBL11210430 | 0.84 | CNKSR1 (0.44) | CNKSR1CYP3A4TTRDPP4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | claimed |
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |