Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646645 | 0.86 | PDE2A (0.49) | PDE2AALDH1A1MAPTEPHX2GPR3 | |
| SCHEMBL1676518 | 0.83 | PDE2A (0.54) | PDE2AALDH1A1MAPTEPHX2L3MBTL1 | |
| SCHEMBL2092438 | 0.82 | PDE2A (0.49) | PDE2AALDH1A1MAPTEPHX2GPR3 | |
| SCHEMBL254957 | 0.80 | MAPT (0.56) | PDE2AALDH1A1MAPTEPHX2GPR3 | |
| SCHEMBL16563355 | 0.79 | PDE2A (0.47) | PDE2AALDH1A1MAPTEPHX2GPR3 | |
| SCHEMBL3484598 | 0.79 | PDE2A (0.50) | PDE2AALDH1A1MAPTEPHX2GPR3 | |
| SCHEMBL1046493 | 0.78 | PDE2A (0.54) | PDE2AALDH1A1MAPTEPHX2L3MBTL1 | |
| SCHEMBL19946330 | 0.78 | PDE2A (0.46) | PDE2AALDH1A1MAPTEPHX2GPR3 | |
| SCHEMBL21497149 | 0.78 | PDE2A (0.42) | PDE2AALDH1A1MAPTEPHX2GPR3 | |
| SCHEMBL4533986 | 0.78 | PDE2A (0.50) | PDE2AALDH1A1SLC7A5L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008854-B1 | PENTADIENONE HYDRAZONE, AND ITS USE AS INSECTICIDAL AGENT | AMERICAN CYANAMID COMPANY (US) | 1983-03-09 | — | — | EP | disclosed |
| EP-0008854-A1 | Pentadienone hydrazone, and its use as insecticidal agent | AMERICAN CYANAMID COMPANY (US) | 1980-03-19 | — | — | EP | disclosed |
| US-4191768-A | Pentadienone hydrazones, method for preparing the same, and insecticidal use thereof | AMERICAN CYANAMID COMPANY (US) | 1980-03-04 | — | — | US | disclosed |