SCHEMBL254957

SCHEMBL254957

FC(F)(F)Oc1ccc(OC(F)(F)F)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
EPHX2 P34913 1/20 0.56
GPR3 P46089 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.48
KDM4E B2RXH2 1/20 0.48
KIF11 P52732 2/20 0.47
PDE2A O00408 1/20 0.47
NISCH Q9Y2I1 1/20 0.47
ALDH1A1 P00352 2/20 0.45
TSHR P16473 2/20 0.45
KMT2A Q03164 2/20 0.45
MAOB P27338 1/20 0.45
AOC3 Q16853 1/20 0.45
MEN1 O00255 1/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45
BLM P54132 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HIF1A Q16665 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28780452 0.91 EPHX2 (0.50) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL255560 0.88 GPR3 (0.52) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL13863723 0.88 MAPT (0.48) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL513525 0.86 MAPT (0.52) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL5073 0.86 TDP1 (0.50) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL97453 0.86 MAPT (0.47) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL7007579 0.86 MAPT (0.47) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL221511 0.86 MAPT (0.52) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL2097243 0.86 MAPT (0.47) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL15372299 0.86 MAPT (0.47) MAPTEPHX2GPR3L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106750301-B Sulfonated polyether sulfone copolymer containing pyridine groups, preparation method and application 中国工程物理研究院化工材料研究所 2019-03-22 CN claimed
CN-106750191-B Sulfonated polyether ketone copolymers of the main chain containing pyridine groups, preparation method and application 中国工程物理研究院化工材料研究所 2018-10-26 CN claimed
CN-105601906-B Sulfonated poly aryl ether ketone cross linking membrane of sulfur-bearing ehter bond and preparation method thereof 中国工程物理研究院化工材料研究所 2018-02-16 CN claimed
CN-106750301-A Sulfonated polyether sulfone copolymer containing pyridine groups, preparation method and application 中国工程物理研究院化工材料研究所 2017-05-31 CN claimed
CN-106750191-A Sulfonated polyether ketone copolymers, preparation method and application of the main chain containing pyridine groups 中国工程物理研究院化工材料研究所 2017-05-31 CN claimed
CN-105601906-A Sulfonated poly aryl ether ketone cross-linking membrane containing thioether keys and preparing method thereof INST CHEMICAL MAT CHINA ACAD ENG PHYSICS 2016-05-25 CN claimed
US-6677379-B2 SUCH AS 3-((3-(3-TRIFLUOROMETHOXYPHENOXY)PHENYL)((3-(1,1,2,2-TETRAFLUOROETHOXY) -PHENYL)METHYL) AMINO)-1,1,1-TRIFLUORO-2-PROPANOL FOR TREATMENT OF CORONARY ARTERY DISEASE PHARMACIA CORPORATION 2004-01-13 US claimed
US-20260088362-A1 ELECTROLYTIC SOLUTION FOR SECONDARY BATTERY, AND SECONDARY BATTERY MURATA MANUFACTURING CO (JP) 2026-03-26 US disclosed
WO-2025013623-A1 ELECTROLYTE SOLUTION FOR SECONDARY BATTERIES, AND SECONDARY BATTERY 株式会社村田製作所 2025-01-16 WO disclosed
US-20230346753-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT VALO HEALTH, INC. 2023-11-02 US disclosed
US-11547701-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2023-01-10 US disclosed
CN-114287077-A Nonaqueous electrolyte solution, battery pack, and method for producing battery pack 旭化成株式会社 2022-04-05 CN disclosed
US-20210244717-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT Valo Health, LLC 2021-08-12 US disclosed
EP-0567848-B1 Process for the alpha-chlorination of arylethern BAYER AG (DE) 1996-07-17 EP disclosed
US-5440051-A Halogenating by metering into reaction vessel at the same time as chlorine in presence of solvent or absence of solvent to form a chemical intermediates for fungicides or insecticides BAYER AKTIENGESELLSCHAFT (DE) 1995-08-08 US disclosed
EP-0567848-A1 Process for the alpha-chlorination of arylethern BAYER AG (DE) 1993-11-03 EP disclosed
EP-0130876-B1 PROCESS FOR THE SIMULTANEOUS HALOGENATION AND FLUORINATION OF AROMATIC COMPOUNDS RHONE-POULENC CHIMIE (FR) 1988-04-20 EP disclosed
US-4575571-A HALOGEN IN LIQUID HYDROGEN FLUORIDE RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1986-03-11 US disclosed
EP-0113625-B1 PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLATED BENZENIC COMPOUNDS RHONE-POULENC CHIMIE (FR) 1985-07-10 EP disclosed
US-4157344-A REACTING PHENOLS WITH A PERHALOMETHANE AND HYDROGEN FLUORIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260088362-A1 ELECTROLYTIC SOLUTION FOR SECONDARY BATTERY, AND SECONDARY BATTERY HCN2, HCN1, PEF1 MAPT 3368/4885EPHX2 1316/4885GPR3 4124/4885
US-11547701-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNMT, NQO1 MAPT 268/4885EPHX2 2810/4885GPR3 2588/4885
US-20210244717-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT NAMPT, NNMT, NQO1 MAPT 519/4885EPHX2 3205/4885GPR3 2010/4885
US-20230346753-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT NAMPT, NNMT, NQO1 MAPT 519/4885EPHX2 3205/4885GPR3 2010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.