Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | PDE1A | P54750 | 1/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281609 | 0.79 | NPC1 (0.48) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL11024247 | 0.78 | MAPT (0.47) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL11024730 | 0.76 | NPC1 (0.41) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL11224141 | 0.75 | ADORA1 (0.52) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL5133464 | 0.68 | MAPT (0.48) | PDE3BPDE3AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29078846 | 0.67 | CYP3A4 (0.58) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL6885360 | 0.67 | KDM4E (0.46) | ALDH1A1KDM4ESMN1; SMN2KMT2AGAA | |
| SCHEMBL27541312 | 0.67 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2KMT2AGAA | |
| SCHEMBL5988684 | 0.67 | ALDH1A1 (0.54) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL1400028 | 0.66 | NR1H2 (0.57) | ALDH1A1KDM4ECYP3A4SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57035573-A | — | — | None | — | — | JP | disclosed |
| JP-S5735573-A | NOVEL 3-ALKYL SUBSTITUTED 2,4(1H,3H)-QUINAZOLINEDIONE DERIVATIVE | ISHIKAWA MASAYUKI | 1982-02-26 | — | — | JP | disclosed |