Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.40 |
| ▸ | GLUL | P15104 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216130 | 1.00 | PTGS1 (0.41) | PTGS1SLC7A11GSRGLULSLC1A1 | |
| SCHEMBL2405601 | 0.88 | PTGS1 (0.46) | PTGS1SLC7A11GSRSLC1A1GRIK1 | |
| SCHEMBL11883461 | 0.83 | GSR (0.42) | PTGS1SLC7A11GSRGLULSLC1A1 | |
| SCHEMBL155324 | 0.80 | GRM8 (0.41) | PTGS1SLC7A11GSRSLC1A1GRIK1 | |
| SCHEMBL11265342 | 0.80 | SLC1A2 (0.42) | PTGS1SLC7A11GSRSLC1A1GRIK1 | |
| SCHEMBL13132158 | 0.80 | GRM8 (0.41) | PTGS1SLC7A11GSRSLC1A1GRIK1 | |
| SCHEMBL1647018 | 0.80 | SLC1A2 (0.42) | PTGS1SLC7A11GSRSLC1A1GRIK1 | |
| SCHEMBL12086544 | 0.80 | SLC1A2 (0.42) | PTGS1SLC7A11GSRSLC1A1GRIK1 | |
| SCHEMBL2729297 | 0.78 | GSR (0.47) | GSRSLC1A1GRIK1GRIK2GRM1 | |
| SCHEMBL13684358 | 0.78 | PTGS1 (0.38) | PTGS1SLC7A11GSRGLULSLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57040409-A | — | — | None | — | — | JP | disclosed |
| JP-S5740409-A | REMEDY FOR DISEASE CAUSED BY EXTRAORDINARY PROPAGATION OF COLLAGEN | MITSUI TOATSU CHEM INC | 1982-03-06 | — | — | JP | disclosed |