Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 7/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 7/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.38 |
| ▸ | GCLC | P48506 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647018 | 1.00 | SLC1A2 (0.42) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL12086544 | 1.00 | SLC1A2 (0.42) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL7211047 | 0.86 | NOS2 (0.41) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL2405601 | 0.86 | PTGS1 (0.46) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL17789223 | 0.83 | GRIK1 (0.41) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL1647262 | 0.83 | GRIK1 (0.41) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL17789224 | 0.80 | SLC1A2 (0.44) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL1158176 | 0.80 | SLC1A2 (0.44) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL11216130 | 0.80 | PTGS1 (0.41) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL11216127 | 0.80 | PTGS1 (0.41) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337247-A | ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-06-29 | — | — | US | claimed |
| US-4337247-A | ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0005248-B1 | TETRAPEPTIDEHYDRAZIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Takeda Chemical Industries, Ltd. (JP) | 1982-03-24 | — | — | EP | disclosed |
| EP-0031567-A2 | Tetrapeptidesemicarbazide derivatives and their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-07-08 | — | — | EP | disclosed |
| US-4277394-A | ANALGESICS, ANTIDIARRHEA, TREATMENT OF MENTAL DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1981-07-07 | — | — | US | disclosed |
| EP-0005248-A2 | Tetrapeptidehydrazide derivatives and process for their preparation | Takeda Chemical Industries, Ltd. (JP) | 1979-11-14 | — | — | EP | disclosed |