Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.38 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ODC1 | P11926 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216164 | 1.00 | GABRR1 (0.38) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL10977090 | 0.71 | ODC1 (0.38) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL11212839 | 0.71 | ODC1 (0.41) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL11208296 | 0.71 | ODC1 (0.38) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL10973685 | 0.71 | ODC1 (0.41) | GABRR1GABRR2BLMGABRR3LMNA | |
| Hydrochloric Acid SCHEMBL11087941 | 0.69 | BLM (0.43) | GABRR1GABRR2BLMGABRR3LMNA | |
| Hydrochloric Acid SCHEMBL11094916 | 0.69 | BLM (0.43) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL11237630 | 0.68 | GABRR1 (0.44) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL11228740 | 0.68 | GABRR1 (0.44) | GABRR1GABRR2BLMGABRR3LMNA | |
| Trifluoroacetic Acid SCHEMBL11205898 | 0.66 | ALDH1A1 (0.47) | GABRR1GABRR2BLMGABRR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399151-A | USING A-SUBSTITUTERD AMINES OR A-SUBSTITUTED AMINO ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4336054-A | AMINO ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-06-22 | — | — | US | disclosed |