SCHEMBL11216169

SCHEMBL11216169

ClCC(Br)n1cc(Cl)cn1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11173904 0.74 HTR2A (0.31)
SCHEMBL16166152 0.70
SCHEMBL4352728 0.70
SCHEMBL2765034 0.68 PLAU (0.30)
SCHEMBL10711431 0.67
SCHEMBL25293350 0.67 ACHE (0.41)
SCHEMBL11333618 0.67 ACHE (0.38) HSD17B10
SCHEMBL25291544 0.67 ACHE (0.41) HSD17B10
SCHEMBL25298957 0.64 ACHE (0.36)
SCHEMBL11346954 0.64 ACHE (0.40) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0008057-B1 PROCESS FOR THE PREPARATION OF N-SUBSTITUTED ALPHA-HALOACETANILIDES BAYER AG (DE) 1982-05-12 EP disclosed
EP-0008056-B1 N-SUBSTITUTED PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND N-HYDROXYALKYLPYRAZOLES OBTAINED IN THE COURSE OF THIS PROCESS BAYER AG (DE) 1981-09-16 EP disclosed
EP-0008091-B1 SUBSTITUTED N-PYRAZOLYLMETHYL-HALOACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AG (DE) 1981-08-12 EP disclosed
EP-0008056-A1 N-substituted pyrazole derivatives, process for their preparation and N-hydroxyalkylpyrazoles obtained in the course of this process BAYER AG (DE) 1980-02-20 EP disclosed
EP-0008091-A1 Substituted N-pyrazolylmethyl-haloacetanilides, process for their preparation and their use as herbicides BAYER AG (DE) 1980-02-20 EP disclosed