Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249506 | 0.92 | HCAR2 (0.40) | CYP19A1MEN1KMT2AHCAR2HCAR3 | |
| SCHEMBL788174 | 0.91 | MEN1 (0.41) | CYP19A1MEN1KMT2AHCAR2HCAR3 | |
| SCHEMBL267262 | 0.73 | ALDH1A1 (0.46) | CYP19A1MEN1KMT2A | |
| SCHEMBL4232967 | 0.73 | ALDH1A1 (0.46) | CYP19A1MEN1KMT2A | |
| SCHEMBL260976 | 0.73 | ALDH1A1 (0.46) | CYP19A1MEN1KMT2A | |
| SCHEMBL18922491 | 0.70 | CYP19A1 (0.42) | CYP19A1 | |
| SCHEMBL21319092 | 0.69 | CYP19A1 (0.32) | CYP19A1CCR2 | |
| SCHEMBL19370854 | 0.68 | MEN1 (0.48) | CYP19A1MEN1KMT2AHCAR2HCAR3 | |
| SCHEMBL13529230 | 0.67 | — | — | |
| SCHEMBL13476642 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57002232-A | — | — | None | — | — | JP | disclosed |
| JP-S572232-A | HYDROXY-8ABETA-METHYL-1-NAPHTHALENONE DERIVATIVE AND ITS PREPARATION | MEIJI SEIKA KAISHA LTD | 1982-01-07 | — | — | JP | disclosed |