SCHEMBL11216422

SCHEMBL11216422

c1ccc(/N=C2/NCc3ccccc32)nc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
HSD17B10 Q99714 2/20 0.39
TP53 P04637 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
ADRA2A P08913 2/20 0.37
ADRA2B P18089 2/20 0.37
ADRA2C P18825 2/20 0.37
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
PLAU P00749 1/20 0.37
MIF P14174 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
PARP1 P09874 1/20 0.33
SLC11A2 P49281 1/20 0.33
NPY5R Q15761 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11040034 1.00 CA12 (0.42) CA12CA9HSD17B10TP53ALOX15
SCHEMBL11022877 0.77 NPC1 (0.35) CA12CA9ALDH1A1L3MBTL1
SCHEMBL31493860 0.77 HSD17B10 (0.44) HSD17B10TP53ALOX15TSHRMAPK1
SCHEMBL9976117 0.77 HSD17B10 (0.44) HSD17B10TP53ALOX15TSHRMAPK1
SCHEMBL3968881 0.77 HSD17B10 (0.44) HSD17B10TP53ALOX15TSHRMAPK1
SCHEMBL3968879 0.77 HSD17B10 (0.44) HSD17B10TP53ALOX15TSHRMAPK1
SCHEMBL4402096 0.75 HSD17B10 (0.43) HSD17B10TP53ALOX15TSHRMAPK1
SCHEMBL4405615 0.75 HSD17B10 (0.43) HSD17B10TP53ALOX15TSHRMAPK1
SCHEMBL4402093 0.75 HSD17B10 (0.43) HSD17B10TP53ALOX15TSHRMAPK1
SCHEMBL4405611 0.75 HSD17B10 (0.43) HSD17B10TP53ALOX15TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0079705-A1 Process for the conversion of an alkane to a mixture of an alcohol and a ketone The British Petroleum Company p.l.c. (GB) 1983-05-25 EP disclosed