Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968881 | 1.00 | HSD17B10 (0.44) | HSD17B10MAPK1TP53ALOX15TSHR | |
| SCHEMBL31493860 | 1.00 | HSD17B10 (0.44) | HSD17B10MAPK1TP53ALOX15TSHR | |
| SCHEMBL9976117 | 1.00 | HSD17B10 (0.44) | HSD17B10MAPK1TP53ALOX15TSHR | |
| SCHEMBL4402093 | 0.98 | HSD17B10 (0.43) | HSD17B10MAPK1TP53ALOX15TSHR | |
| SCHEMBL4405611 | 0.98 | HSD17B10 (0.43) | HSD17B10MAPK1TP53ALOX15TSHR | |
| SCHEMBL4402096 | 0.98 | HSD17B10 (0.43) | HSD17B10MAPK1TP53ALOX15TSHR | |
| SCHEMBL4405615 | 0.98 | HSD17B10 (0.43) | HSD17B10MAPK1TP53ALOX15TSHR | |
| SCHEMBL26453690 | 0.88 | GSK3B (0.45) | HSD17B10MAPK1TP53ALOX15TSHR | |
| SCHEMBL4074981 | 0.85 | MAPT (0.38) | HSD17B10MAPK1TP53ALOX15TSHR | |
| SCHEMBL21715832 | 0.85 | MAPT (0.38) | HSD17B10MAPK1TP53ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427759-B1 | TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION | EQUISTAR CHEM LP (US) | 2009-12-23 | — | — | EP | claimed |
| EP-1699834-B1 | LTMC POLYMERIZATION OF UNSATURATED MONOMERS | EQUISTAR CHEM LP (US) | 2008-10-29 | — | — | EP | claimed |
| EP-1694723-B1 | PREPARATION OF OLEFIN-ACRYLIC COPOLYMERS WITH LATE TRANSITION METAL CATALYSTS | EQUISTAR CHEM LP (US) | 2007-05-02 | — | — | EP | claimed |
| EP-1699834-A1 | LTMC POLYMERIZATION OF UNSATURATED MONOMERS | Equistar Chemicals, LP (US) | 2006-09-13 | — | — | EP | claimed |
| WO-2005066225-A1 | LTMC POLYMERIZATION OF UNSATURATED MONOMERS | EQUISTAR CHEMICALS, LP (US) | 2005-07-21 | — | — | WO | claimed |
| US-20050143537-A1 | LTMC POLYMERIZATION OF UNSATURATED MONOMERS | EQUISTAR CHEMICALS, LP | 2005-06-30 | — | — | US | claimed |
| US-6903169-B1 | LTMC polymerization of unsaturated monomers | EQUISTAR CHEMICALS, LP (US) | 2005-06-07 | — | — | US | claimed |
| US-6844402-B1 | Preparation of olefin-acrylic copolymers with late transition metal catalysts | EQUISTAR CHEMICALS, LP (US) | 2005-01-18 | — | — | US | claimed |
| US-6693154-B2 | AN ORGANOMETALLIC COMPLEX CONTAINS A TRANSITION OR LANTHANIDE METAL AND 1,3-BIS(ARYLIMINO)ISOINDOLINE OR 1,3-BIS(HETEROARYLIMINO) ISOINDOLINE; ETHYLENE COPOLYMER WITH HIGH MOLECULAR WEIGHT, BROAD MOLECULAR WEIGHT DISTRIBUTION | EQUISTAR CHEMICALS, LP | 2004-02-17 | — | — | US | claimed |
| US-20030065113-A1 | Transition metal catalysts for olefin polymerization | EQUISTAR CHEMICALS, LP | 2003-04-03 | — | — | US | claimed |
| EP-0270468-B1 | PROCESS FOR PREPARING A MIXTURE CONTAINING CYCLOHEXANOL AND CYCLOHEXANONE FROM CYCLOHEXANE | RHONE-POULENC CHIMIE (FR) | 1991-07-24 | — | — | EP | claimed |
| US-4499305-A | FORMING STABLE DISPERSIONS OF A TRANSITION METAL COMPLEX AND 1,3-BIS/2-PYRIDYLIMINO/ISOINDOLINE IN CYCLOHEXANOL, CYCLOHEXANONE AND/OR CYCLOHEXANE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-02-12 | — | — | US | claimed |
| US-10577387-B1 | Platinum (II) complexes containing N-heterocyclic carbene ligand and pincer ligands, synthesis, and their applications in cancer treatment | THE UNIVERSITY OF HONG KONG (CN) | 2020-03-03 | — | — | US | disclosed |
| US-20200048291-A1 | PLATINUM (II) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND AND PINCER LIGANDS, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT | VERSITECH LIMITED (CN) | 2020-02-13 | — | — | US | disclosed |
| US-9412955-B2 | Fluorescent isoindoline dyes | UNIVERSAL DISPLAY CORPORATION (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150318494-A1 | Fluorescent Isoindoline Dyes | UNIV SOUTHERN CALIFORNIA (US) | 2015-11-05 | — | — | US | disclosed |
| EP-0048024-A1 | Improved process for producing 1,3-bis(2-pyridylimino)isoindolines and compositions containing transition metal complexes thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0048024-A1 | Improved process for producing 1,3-bis(2-pyridylimino)isoindolines and compositions containing transition metal complexes thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0027937-A1 | Improved process for producing a mixture containing cyclohexanol and cyclohexanone from cyclohexane | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-06 | — | — | EP | disclosed |
| EP-0027937-A1 | Improved process for producing a mixture containing cyclohexanol and cyclohexanone from cyclohexane | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048291-A1 | PLATINUM (II) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND AND PINCER LIGANDS, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT | PIN4, PAICS, PIN1 | HSD17B10 3631/4885MAPK1 3910/4885TP53 13/4885 |
| US-20150318494-A1 | Fluorescent Isoindoline Dyes | OCIAD1, OCIAD2, OXA1L | HSD17B10 1507/4885MAPK1 4155/4885TP53 2470/4885 |
| US-10577387-B1 | Platinum (II) complexes containing N-heterocyclic carbene ligand and pincer ligands, synthesis, and their applications in cancer treatment | PIN4, PAICS, PIN1 | HSD17B10 3631/4885MAPK1 3910/4885TP53 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.