Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 4/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 13/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453293 | 0.89 | KCNE1 (0.39) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL11461359 | 0.85 | ABCB1 (0.37) | KCNE1KCNQ1ABCB1 | |
| SCHEMBL11444000 | 0.84 | ABCB1 (0.38) | CYP1A2CYP2D6CYP2C19ABCB1ABCC9 | |
| SCHEMBL11444447 | 0.81 | ABCB1 (0.39) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL11444455 | 0.81 | ABCB1 (0.39) | ABCB1 | |
| SCHEMBL9066178 | 0.80 | AKR1B1 (0.37) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL11444446 | 0.80 | KDM4E (0.42) | CYP1A2CYP3A4CYP2D6CYP2C19ABCB1 | |
| SCHEMBL11451772 | 0.79 | KCNE1 (0.38) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL11319914 | 0.78 | GAA (0.47) | — | |
| SCHEMBL13492306 | 0.77 | PDK2 (0.38) | MEN1CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | claimed |
| US-4333759-A | Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones | FISONS LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |