Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | DBH | P09172 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216729 | 1.00 | JUN (0.70) | JUNMAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL17693076 | 0.90 | JUN (0.71) | JUNMAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL3198145 | 0.89 | JUN (0.81) | JUNMAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL3198139 | 0.89 | JUN (0.81) | JUNMAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL6035429 | 0.88 | JUN (0.75) | JUNMAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL17518839 | 0.88 | EPHX2 (0.56) | JUNMAPTLMNAGAAHTT | |
| SCHEMBL17504463 | 0.88 | JUN (0.75) | JUNMAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL6035433 | 0.88 | JUN (0.75) | JUNMAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL11212525 | 0.87 | JUN (0.64) | JUNMAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL11212526 | 0.87 | JUN (0.64) | JUNMAPTSMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |