Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.64 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.64 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL29170957 | 0.98 | CRBN (0.67) | CRBNFKBP5OR51E2KDM4ESMN1; SMN2 | |
| Biphenyl SCHEMBL29191183 | 0.98 | CRBN (0.67) | CRBNFKBP5OR51E2KDM4ESMN1; SMN2 | |
| Biphenyl SCHEMBL27737523 | 0.92 | OR51E2 (0.65) | CRBNFKBP5OR51E2KDM4ESMN1; SMN2 | |
| Caprolactam SCHEMBL17986693 | 0.89 | CRBN (0.80) | CRBNFKBP5OR51E2KDM4ESMN1; SMN2 | |
| SCHEMBL29030288 | 0.89 | FKBP5 (0.59) | CRBNFKBP5OR51E2KDM4ESMN1; SMN2 | |
| Caprolactam SCHEMBL27637449 | 0.87 | CRBN (0.76) | CRBNFKBP5OR51E2KDM4ESMN1; SMN2 | |
| Caprolactam SCHEMBL27671749 | 0.85 | FKBP5 (0.59) | CRBNFKBP5OR51E2KDM4ESMN1; SMN2 | |
| Caprolactam SCHEMBL7069031 | 0.85 | FKBP5 (0.59) | CRBNFKBP5OR51E2KDM4ESMN1; SMN2 | |
| Toluene SCHEMBL27907611 | 0.85 | FKBP5 (0.59) | CRBNFKBP5OR51E2KDM4ESMN1; SMN2 | |
| Naphthalene SCHEMBL28222377 | 0.83 | CRBN (0.70) | CRBNFKBP5OR51E2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323491-A | POLYDIETHYLENE ADIPATE-TOLUENE DIISOCYANATE POLY-ESTERURETHANE, WATER, UREA, SODIUM SULFORICINATE | VESELOVSKY ROMAN A | 1982-04-06 | — | — | US | disclosed |