Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.74 |
| ▸ | PGR | P06401 | 3/20 | 0.74 |
| ▸ | PPARG | P37231 | 2/20 | 0.74 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.74 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.74 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.74 |
| ▸ | DAO | P14920 | 1/20 | 0.74 |
| ▸ | SNCA | P37840 | 1/20 | 0.74 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.74 |
| ▸ | HTR2C | P28335 | 1/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | ALB | P02768 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.63 |
| ▸ | APEX1 | P27695 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23051167 | 0.91 | NR1I2 (0.77) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL23043566 | 0.91 | NR1I2 (0.77) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL9684932 | 0.90 | NR1I2 (0.75) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL9683674 | 0.89 | NR1I2 (0.79) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL8869035 | 0.88 | NR1I2 (0.83) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL8869018 | 0.88 | NR1I2 (0.83) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL13900618 | 0.88 | NR1I2 (0.83) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL8988439 | 0.88 | NR1I2 (0.73) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL9845713 | 0.88 | NR1I2 (0.73) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10529854 | 0.88 | NR1I2 (0.74) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57059895-A | — | — | None | — | — | JP | disclosed |
| JP-S5759895-A | 7-BETA-(ALPHA-SYN-METHOXYIMINO-ALPHA-(2- AMINOTHIAZOL-4-YL)-ACETAMIDO)-3-((1,2,3- THIAZOL-5-YL-THIO)METHYL)-3-CEPHEM-4-CARBOXYLIC ACID AND C1-C6 ALKYL DERIVATIVE THEREOF | AMERICAN CYANAMID CO | 1982-04-10 | — | — | JP | disclosed |