Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.77 |
| ▸ | HTR2C | P28335 | 1/20 | 0.77 |
| ▸ | PGR | P06401 | 3/20 | 0.77 |
| ▸ | PPARG | P37231 | 2/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.75 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.75 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | DAO | P14920 | 1/20 | 0.75 |
| ▸ | SNCA | P37840 | 1/20 | 0.75 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | ALB | P02768 | 1/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.65 |
| ▸ | APEX1 | P27695 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043566 | 1.00 | NR1I2 (0.77) | NR1I2HTR2CPGRPPARGSLC22A6 | |
| SCHEMBL9684932 | 0.94 | NR1I2 (0.75) | NR1I2HTR2CPGRPPARGSLC22A6 | |
| SCHEMBL8988439 | 0.93 | NR1I2 (0.73) | NR1I2HTR2CPGRPPARGSLC22A6 | |
| SCHEMBL9845713 | 0.93 | NR1I2 (0.73) | NR1I2HTR2CPGRPPARGSLC22A6 | |
| SCHEMBL10529854 | 0.92 | NR1I2 (0.74) | NR1I2HTR2CPGRPPARGSLC22A6 | |
| SCHEMBL9845743 | 0.92 | NR1I2 (0.71) | NR1I2HTR2CPGRPPARGSLC22A6 | |
| SCHEMBL8988378 | 0.92 | NR1I2 (0.71) | NR1I2HTR2CPGRPPARGSLC22A6 | |
| SCHEMBL9683674 | 0.91 | NR1I2 (0.79) | NR1I2HTR2CPGRPPARGSLC22A6 | |
| SCHEMBL9683389 | 0.91 | NR1I2 (0.72) | NR1I2HTR2CPGRPPARGSLC22A6 | |
| SCHEMBL11216841 | 0.91 | NR1I2 (0.74) | NR1I2HTR2CPGRPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177947-A1 | Compounds to Identify Beta-Lactamases, and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-06-09 | — | — | US | disclosed |
| WO-2021041583-A1 | COMPOUNDS TO IDENTIFY BETA-LACTAMASES, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177947-A1 | Compounds to Identify Beta-Lactamases, and Methods of Use Thereof | GUSB, GLB1, MGAM | NR1I2 3639/4885HTR2C 4318/4885PGR 4662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.