Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 11/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24954142 | 0.74 | — | — | |
| SCHEMBL10910728 | 0.68 | SMN1; SMN2 (0.37) | CRHR1SMN1; SMN2NPY5RSLC29A1MAP2K7 | |
| SCHEMBL9127003 | 0.65 | SMN1; SMN2 (0.42) | CRHR1HTTSMN1; SMN2NPY5RSLC29A1 | |
| SCHEMBL13764999 | 0.62 | ALDH1A1 (0.36) | CRHR1HTTSMN1; SMN2NPY5RMAP2K7 | |
| SCHEMBL14461779 | 0.61 | — | — | |
| SCHEMBL23937936 | 0.61 | IDO1 (0.39) | HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10671138 | 0.61 | SMN1; SMN2 (0.39) | CRHR1HTTSMN1; SMN2NPY5RSLC29A1 | |
| SCHEMBL24649607 | 0.60 | ACP1 (0.66) | HTTSMN1; SMN2NPY5RPDGFRBKDR | |
| SCHEMBL23176058 | 0.59 | — | — | |
| SCHEMBL9123231 | 0.58 | SMN1; SMN2 (0.37) | CRHR1HTTSMN1; SMN2NPY5RSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57035591-A | — | — | None | — | — | JP | disclosed |
| JP-S5735591-A | NOVEL PYRIMIDINE DERIVATIVE | MOCHIDA PHARMACEUT CO LTD | 1982-02-26 | — | — | JP | disclosed |