SCHEMBL11217528

SCHEMBL11217528

C=CC(OC(C)=O)OC(=O)CC#N

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7976584 0.85 TSHR (0.33) TSHR
SCHEMBL5143110 0.83 TSHR (0.32) TSHR
SCHEMBL992095 0.79 TSHR (0.46) TSHR
SCHEMBL11440716 0.74 TSHR (0.39) MCL1TSHR
SCHEMBL11216042 0.74 MCL1 (0.33) MCL1
SCHEMBL7771732 0.71 TSHR (0.39) TSHR
SCHEMBL29164011 0.71 TSHR (0.42) TSHR
SCHEMBL1421343 0.70
SCHEMBL7644505 0.70 TSHR (0.38) TSHR
SCHEMBL8744171 0.69 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4202836-A Acetoxyalkyl cyanoacetate intermediates in the manufacture of copolymerizable, ultraviolet light absorber compounds GAF CORPORATION (US) 1980-05-13 US claimed
EP-0026339-B1 RADIATION CURABLE COATING COMPOSITION AND PROCESS FOR COATING A SUBSTRATE THEREWITH GAF CORPORATION (US) 1983-11-30 EP disclosed
US-4276136-A Radiation curable coating composition comprising an ethylenically unsaturated oligomer and an ethylenically unsaturated copolymerizable ultra-violet absorber GAF CORPORATION (US) 1981-06-30 US disclosed
US-4263366-A Radiation curable coating composition comprising an oligomer and a copolymerizable ultra-violet absorber GAF CORPORATION (US) 1981-04-21 US disclosed
EP-0026339-A1 Radiation curable coating composition and process for coating a substrate therewith GAF CORPORATION (US) 1981-04-08 EP disclosed
EP-0017703-A1 Copolymerizable (2-cyano-3,3-diarylacryloxy)alkylene compounds, a method of making them and the use of these compounds as ultraviolet light absorbers GAF CORPORATION (US) 1980-10-29 EP disclosed
US-4207253-A Method of making copolymerizable, ultraviolet light absorber (2-cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1980-06-10 US disclosed
US-4203919-A (Acetoxyalkyl) 2-cyano-3,3-diphenylacrylate intermediates for making copolymerizable, ultraviolet light absorber compounds GAF CORPORATION (US) 1980-05-20 US disclosed
US-4202834-A Copolymerizable, ultraviolet light absorber (2-cyano-3,3-diphenylacryloxy) alkylene ethylenic ethers GAF CORPORATION (US) 1980-05-13 US disclosed
US-4202836-A Acetoxyalkyl cyanoacetate intermediates in the manufacture of copolymerizable, ultraviolet light absorber compounds GAF CORPORATION (US) 1980-05-13 US disclosed
US-4202836-A Acetoxyalkyl cyanoacetate intermediates in the manufacture of copolymerizable, ultraviolet light absorber compounds GAF CORPORATION (US) 1980-05-13 US disclosed
US-4202836-A Acetoxyalkyl cyanoacetate intermediates in the manufacture of copolymerizable, ultraviolet light absorber compounds GAF CORPORATION (US) 1980-05-13 US disclosed
US-4178303-A (2-Cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1979-12-11 US disclosed