SCHEMBL1421343

SCHEMBL1421343

[CH2]C(C)OC(=O)CC#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1170737 0.82
SCHEMBL11447784 0.80
SCHEMBL6748118 0.80 LMNA (0.41)
SCHEMBL28416408 0.78
SCHEMBL22321687 0.78 MCL1 (0.37)
SCHEMBL10396862 0.78 MCL1 (0.37)
SCHEMBL28913780 0.78
SCHEMBL28137608 0.78 MCL1 (0.37)
SCHEMBL7990753 0.77 MCL1 (0.35)
SCHEMBL1336184 0.77 MCL1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9938424-B2 Coating compositions for improved block resistance ARKEMA INC. (US) 2018-04-10 US claimed
US-20170009095-A1 COATING COMPOSITIONS FOR IMPROVED BLOCK RESISTANCE ARKEMA INC (US) 2017-01-12 US claimed
EP-2297258-B1 COATING COMPOSITIONS HAVING INCREASED BLOCK RESISTANCE ARKEMA INC (US) 2014-03-19 EP claimed
EP-2297258-A1 COATING COMPOSITIONS HAVING INCREASED BLOCK RESISTANCE Arkema, Inc. (US) 2011-03-23 EP claimed
WO-2010005511-A1 COATING COMPOSITIONS HAVING INCREASED BLOCK RESISTANCE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2010-01-14 WO claimed
US-9938424-B2 Coating compositions for improved block resistance ARKEMA INC. (US) 2018-04-10 US disclosed
US-20170009095-A1 COATING COMPOSITIONS FOR IMPROVED BLOCK RESISTANCE ARKEMA INC (US) 2017-01-12 US disclosed
US-9475953-B2 Coating compositions for improved block resistance ARKEMA INC. (US) 2016-10-25 US disclosed
US-20150152280-A1 COATING COMPOSITIONS FOR IMPROVED BLOCK RESISTANCE ARKEMA INC. (US) 2015-06-04 US disclosed
EP-2297258-B1 COATING COMPOSITIONS HAVING INCREASED BLOCK RESISTANCE ARKEMA INC (US) 2014-03-19 EP disclosed
EP-2297258-A1 COATING COMPOSITIONS HAVING INCREASED BLOCK RESISTANCE Arkema, Inc. (US) 2011-03-23 EP disclosed
WO-2010005511-A1 COATING COMPOSITIONS HAVING INCREASED BLOCK RESISTANCE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) 2010-01-14 WO disclosed