SCHEMBL1121797

SCHEMBL1121797

CCC(CO)(CO)COC(=O)c1cc(C(=O)O)ccc1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 3/20 0.40
MAPK1 P28482 2/20 0.40
TSHR P16473 2/20 0.40
HIF1A Q16665 1/20 0.40
LMNA P02545 1/20 0.37
RAB9A P51151 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
ACE2 Q9BYF1 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
PTPN11 Q06124 2/20 0.36
CDC25A P30304 1/20 0.36
CDC25B P30305 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MYC P01106 1/20 0.35
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 1/20 0.35
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1121795 0.90 MAPK1 (0.44) KDM4EALDH1A1MAPK1TSHRHIF1A
SCHEMBL5936377 0.84 KDM4E (0.49) KDM4EALDH1A1TSHRLMNARAB9A
SCHEMBL29362222 0.84 KDM4E (0.49) KDM4EALDH1A1TSHRLMNARAB9A
SCHEMBL1104259 0.83 KDM4E (0.43) KDM4EALDH1A1MAPK1TSHRHIF1A
SCHEMBL11372672 0.83 KDM4E (0.43) KDM4EALDH1A1MAPK1TSHRHIF1A
SCHEMBL16248492 0.83 ALDH1A1 (0.51) ALDH1A1MAPK1TSHRHIF1ALMNA
SCHEMBL11517150 0.83 MAPK1 (0.54) ALDH1A1MAPK1TSHRHIF1ALMNA
SCHEMBL21561621 0.81 MAPT (0.44) KDM4EALDH1A1MAPK1TSHRHIF1A
Ethylene Glycol SCHEMBL5687572 0.81 KDM4E (0.43) KDM4EALDH1A1MAPK1TSHRHIF1A
SCHEMBL11853878 0.81 MAPK1 (0.53) ALDH1A1MAPK1HIF1ALMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10035910-B2 Polymer composition and heat-shrinkable article TYCO ELECTRONICS UK LTD (GB) 2018-07-31 US claimed
EP-3149076-B1 POLYMER COMPOSITION AND HEAT-SHRINKABLE ARTICLE TYCO ELECTRONICS LTD UK (GB) 2018-03-14 EP claimed
EP-3149076-A1 POLYMER COMPOSITION AND HEAT-SHRINKABLE ARTICLE Tyco Electronics UK Ltd. (GB) 2017-04-05 EP claimed
US-20170073514-A1 Polymer Composition and Heat-Shrinkable Article TYCO ELECTRONICS UK LTD (GB) 2017-03-16 US claimed
WO-2015180899-A1 POLYMER COMPOSITION AND HEAT-SHRINKABLE ARTICLE TYCO ELECTRONICS UK LTD (GB) 2015-12-03 WO claimed
US-7786205-B2 Foamable adhesive composition TYCO ELECTRONICS CORPORATION (US) 2010-08-31 US claimed
US-20070185278-A1 Foamable coupling for lamp assembly and methods for using the coupling TYCO ELECTRONICS CORPORATION (US) 2007-08-09 US claimed
EP-1656419-A1 COMPOSITIONS FOR HEAT-RECOVERABLE FOAM TUBING Tyco Electronics Corporation (US) 2006-05-17 EP claimed
WO-2005017027-A1 COMPOSITIONS FOR HEAT-RECOVERABLE FOAM TUBING TYCO ELECTRONICS CORPORATION (US) 2005-02-24 WO claimed
US-20050031811-A1 Heat shrinkage mixture of polymer and blowing agent; heat activation encapsulated in shell TE CONNECTIVITY SOLUTIONS GMBH (CH) 2005-02-10 US claimed
US-12215246-B2 Composition comprising a light-weight filler HENKEL AG & CO. KGAA (DE) 2025-02-04 US disclosed
US-20240132687-A1 Thermally expandable compositions comprising wax HENKEL AG & CO KGAA (DE) 2024-04-25 US disclosed
CN-113692421-B Pumpable, thermally curable and expandable formulation 汉高股份有限及两合公司 2024-03-08 CN disclosed
CN-117616074-A Thermally expandable composition comprising wax 汉高股份有限及两合公司 2024-02-27 CN disclosed
US-11834565-B2 Shape memory products and method for making them TYCO ELECTRONICS UK LTD. (GB) 2023-12-05 US disclosed
WO-1999037506-A1 CAVITY SEALING ARTICLE AND METHOD TYCO ELECTRONICS CORPORATION (US) 1999-07-29 WO disclosed
WO-1999006479-A1 HIGH VOLTAGE ELECTRICAL INSULATION MATERIAL RAYCHEM LIMITED (GB) 1999-02-11 WO disclosed
WO-1998036944-A1 CAVITY SEALING ARTICLE AND METHOD RAYCHEM CORPORATION (US) 1998-08-27 WO disclosed
EP-0627463-A2 Flame retardant resin composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1994-12-07 EP disclosed
US-4160753-A FROM POLYAMINES AND POLYISOCYANATES BAYER AKTIENGESELLSCHAFT (DE) 1979-07-10 US disclosed