Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.89 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 4/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13160185 | 0.86 | DRD2 (0.70) | DRD2DRD3HTR1AHTR2AHRH1 | |
| SCHEMBL10665994 | 0.85 | DRD2 (0.71) | DRD2DRD1DRD3HTR1AHTR2A | |
| SCHEMBL23097791 | 0.84 | DRD2 (0.66) | DRD2DRD1DRD3HTR1AHTR2A | |
| SCHEMBL253846 | 0.84 | DRD2 (0.90) | DRD2DRD1DRD3 | |
| SCHEMBL10668573 | 0.83 | DRD3 (0.71) | DRD2DRD3HTR1AHTR2AHRH1 | |
| SCHEMBL6825803 | 0.82 | DRD2 (1.00) | DRD2DRD1DRD3 | |
| SCHEMBL722220 | 0.82 | DRD2 (0.68) | DRD2DRD1DRD3HTR1AHTR2A | |
| SCHEMBL3410913 | 0.81 | DRD2 (1.00) | DRD2DRD1DRD3HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL10568463 | 0.81 | DRD2 (0.66) | DRD2DRD3HTR1AHTR2AHRH1 | |
| SCHEMBL252086 | 0.81 | DRD2 (0.88) | DRD2DRD1DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57009769-A | — | — | None | — | — | JP | disclosed |
| JP-S579769-A | 2-BENZIMIDAZOLINONE DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1982-01-19 | — | — | JP | disclosed |