Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 12/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461737 | 0.91 | ESR1 (0.67) | ESR1ESR2HRH4HRH3SLC8A1 | |
| SCHEMBL27849981 | 0.91 | ESR1 (0.67) | ESR1ESR2HRH4HRH3SLC8A1 | |
| SCHEMBL11053683 | 0.85 | ESR1 (0.60) | ESR1ESR2MAOBHRH3 | |
| SCHEMBL11053787 | 0.85 | ESR1 (0.59) | ESR1ESR2SLC8A1 | |
| SCHEMBL11049466 | 0.85 | ESR1 (0.56) | ESR1ESR2MAOBSLC8A1RAB9A | |
| SCHEMBL11225542 | 0.82 | ESR1 (0.56) | ESR1ESR2MAOB | |
| SCHEMBL3487847 | 0.82 | ESR1 (0.56) | ESR1ESR2MAOBHRH4HRH3 | |
| SCHEMBL11232934 | 0.80 | ESR1 (0.54) | ESR1ESR2MAOBRAB9AKMT2A | |
| SCHEMBL11050068 | 0.79 | ESR1 (0.60) | ESR1ESR2SLC8A1 | |
| SCHEMBL11053684 | 0.79 | ESR1 (0.60) | ESR1ESR2MAOBHRH3SLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004579-B1 | FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-08-18 | — | — | EP | claimed |
| EP-0004579-A1 | Flavans, process for their preparation and pharmaceutical compositions containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-10-17 | — | — | EP | claimed |
| EP-0004579-B1 | FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-08-18 | — | — | EP | disclosed |
| EP-0051061-A2 | Novel intermediates and process for their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-05-05 | — | — | EP | disclosed |
| EP-0004579-A1 | Flavans, process for their preparation and pharmaceutical compositions containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-10-17 | — | — | EP | disclosed |