Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | SLC8A1 | P32418 | 7/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3488386 | 0.92 | ESR1 (0.56) | ESR1ESR2HCRTR2SLC8A1MAOA | |
| SCHEMBL11048933 | 0.89 | ESR1 (0.57) | ESR1ESR2SLC8A1CYP19A1 | |
| SCHEMBL4461737 | 0.87 | ESR1 (0.67) | ESR1ESR2SLC8A1HRH4HRH3 | |
| SCHEMBL27849981 | 0.87 | ESR1 (0.67) | ESR1ESR2SLC8A1HRH4HRH3 | |
| SCHEMBL11219441 | 0.82 | ESR1 (0.60) | ESR1ESR2SLC8A1MAOBKMT2A | |
| SCHEMBL11053683 | 0.82 | ESR1 (0.60) | ESR1ESR2MAOBHRH3 | |
| SCHEMBL11053787 | 0.81 | ESR1 (0.59) | ESR1ESR2SLC8A1SMN1; SMN2 | |
| SCHEMBL11049466 | 0.78 | ESR1 (0.56) | ESR1ESR2SLC8A1CYP19A1MAOB | |
| SCHEMBL11050068 | 0.76 | ESR1 (0.60) | ESR1ESR2SLC8A1 | |
| SCHEMBL11053684 | 0.76 | ESR1 (0.60) | ESR1ESR2SLC8A1MAOBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200087630-A1 | INFLUENZA VIRUS AND TYPE 1 DIABETES | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2020-03-19 | — | — | US | disclosed |
| US-20180273912-A1 | INFLUENZA VIRUS AND TYPE 1 DIABETES | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2018-09-27 | — | — | US | disclosed |
| US-20150299667-A1 | INFLUENZA VIRUS AND TYPE 1 DIABETES | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2015-10-22 | — | — | US | disclosed |
| EP-2906231-A2 | INFLUENZA VIRUS AND TYPE 1 DIABETES | Ospedale San Raffaele S.r.l. (IT) | 2015-08-19 | — | — | EP | disclosed |
| US-20100047273-A1 | Coxsackie B virus and type 1 diabetes | RAPPUOLI RINO | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047273-A1 | Coxsackie B virus and type 1 diabetes | IAPP, IRS1, RNASE1 | ESR1 3889/4885ESR2 2792/4885HCRTR2 4076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.