Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.63 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.63 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.63 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11219449 | 1.00 | TDP1 (0.78) | TDP1MAPK1CTDSP1MAPTNR1I2 | |
| SCHEMBL11225238 | 0.89 | TDP1 (0.84) | TDP1MAPK1CTDSP1MAPTNR1I2 | |
| SCHEMBL11224167 | 0.89 | TDP1 (0.84) | TDP1MAPK1CTDSP1MAPTNR1I2 | |
| SCHEMBL11225245 | 0.89 | TDP1 (0.84) | TDP1MAPK1CTDSP1MAPTNR1I2 | |
| SCHEMBL11224172 | 0.89 | TDP1 (0.84) | TDP1MAPK1CTDSP1MAPTNR1I2 | |
| SCHEMBL11223627 | 0.88 | TDP1 (0.81) | TDP1MAPK1CTDSP1MAPTNR1I2 | |
| SCHEMBL11223624 | 0.88 | TDP1 (0.81) | TDP1MAPK1CTDSP1MAPTNR1I2 | |
| Cefaloram SCHEMBL10428695 | 0.88 | TDP1 (1.00) | TDP1MAPK1CTDSP1MAPTNR1I2 | |
| Cefaloram SCHEMBL11057775 | 0.88 | TDP1 (1.00) | TDP1MAPK1CTDSP1MAPTNR1I2 | |
| SCHEMBL14300064 | 0.88 | TDP1 (0.82) | TDP1MAPK1CTDSP1MAPTNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323676-A | Process for preparing cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4308381-A | Cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4245088-A | Novel 3-acyloxymethyl-cephem compounds useful as intermediates for preparing cephalosporin antibiotics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | disclosed |