Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398167 | 0.86 | GRIK1 (0.35) | GRIK1GRIK2CPA1ALDH1A1 | |
| SCHEMBL11226676 | 0.84 | GRIK1 (0.43) | GRIK1GRIK2CPA1ALDH1A1CYP2C19 | |
| SCHEMBL6048423 | 0.78 | GRIK1 (0.50) | GRIK1GRIK2 | |
| SCHEMBL6048425 | 0.78 | GRIK1 (0.50) | GRIK1GRIK2 | |
| SCHEMBL4346549 | 0.77 | GRIK1 (0.51) | GRIK1GRIK2ALDH1A1TDP1 | |
| SCHEMBL4346550 | 0.77 | GRIK1 (0.51) | GRIK1GRIK2ALDH1A1TDP1 | |
| SCHEMBL891727 | 0.76 | GRIK1 (0.64) | GRIK1GRIK2CPA1CYP2C19TDP1 | |
| SCHEMBL20788028 | 0.76 | FOLH1 (0.43) | CPA1TDP1 | |
| SCHEMBL21218827 | 0.76 | CA2 (0.42) | ALDH1A1TDP1 | |
| SCHEMBL10378555 | 0.76 | CA2 (0.42) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332694-A | IMMOBILIZATION OF ENZYMES | CESKOSLOVENSKA AKADEMIE VED (CS) | 1982-06-01 | — | — | US | claimed |
| US-4332694-A | IMMOBILIZATION OF ENZYMES | CESKOSLOVENSKA AKADEMIE VED (CS) | 1982-06-01 | — | — | US | disclosed |