Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Itaconic Anhydride SCHEMBL11359825 | 0.86 | DDB1 (0.38) | CRBNDDB1MAPTPOLBALDH1A1 | |
| SCHEMBL11754494 | 0.83 | DDB1 (0.47) | CRBNDDB1MAPTALDH1A1HPGD | |
| SCHEMBL10960844 | 0.83 | NR1H2 (0.34) | CRBNDDB1MAPTALDH1A1HPGD | |
| SCHEMBL4459810 | 0.82 | DDB1 (0.44) | CRBNDDB1MAPTPOLBALDH1A1 | |
| SCHEMBL11757714 | 0.81 | DDB1 (0.51) | CRBNDDB1MAPTPOLBALDH1A1 | |
| SCHEMBL19463659 | 0.79 | DDB1 (0.51) | CRBNDDB1ALDH1A1HPGD | |
| SCHEMBL11755863 | 0.73 | LDHA (0.38) | MAPT | |
| SCHEMBL877603 | 0.72 | POLB (0.53) | CRBNDDB1MAPTPOLBALDH1A1 | |
| SCHEMBL11756918 | 0.71 | DDB1 (0.51) | CRBNDDB1MAPTPOLBALDH1A1 | |
| SCHEMBL10690598 | 0.69 | MEN1 (0.55) | MAPTPOLBALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323676-A | Process for preparing cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | claimed |
| US-4323676-A | Process for preparing cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4308381-A | Cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4245088-A | Novel 3-acyloxymethyl-cephem compounds useful as intermediates for preparing cephalosporin antibiotics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | disclosed |
| US-4009278-A | Antimicrobial composition and method containing N-(3,5-dihalophenyl)-imide compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-02-22 | — | — | US | disclosed |