Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.54 |
| ▸ | PREP | P48147 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6051964 | 0.93 | ACE (0.55) | ACEPREPMEN1TSHRHTT | |
| SCHEMBL19084116 | 0.93 | ACE (0.55) | ACEPREPMEN1TSHRHTT | |
| SCHEMBL11378012 | 0.80 | ACE (0.56) | ACEPREP | |
| SCHEMBL6052009 | 0.80 | ACE (0.53) | ACEPREPDPP4DPP8DPP7 | |
| SCHEMBL11486007 | 0.80 | ACE (0.59) | ACEPREP | |
| SCHEMBL11392768 | 0.80 | ACE (0.59) | ACEPREP | |
| SCHEMBL11381314 | 0.79 | ACE (0.54) | ACEPREPDPP4DPP8DPP7 | |
| SCHEMBL10940644 | 0.78 | ACE (0.53) | ACEPREPDPP4DPP8DPP7 | |
| SCHEMBL20718946 | 0.77 | ACE (0.53) | ACEPREPKMT2ADPP4DPP8 | |
| SCHEMBL31590738 | 0.76 | ACE (0.51) | ACEPREPKMT2ADPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57058677-A | — | — | None | — | — | JP | disclosed |
| JP-S5758677-A | GERMANIUM COMPOUND OF THIAZOLIDINE DERIVATIVE AND ITS PREPARATION | SANKYO CO LTD | 1982-04-08 | — | — | JP | disclosed |