SCHEMBL11220504

SCHEMBL11220504

C=CC[Si](CC=C)(CC=C)N=C1NC(=O)NC1=O

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
OGT O15294 1/20 0.31
USP2 O75604 1/20 0.31
MAPT P10636 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11220502 1.00 KDM4E (0.31) KDM4EOGTUSP2MAPTRECQL
SCHEMBL7401749 0.64 KDM4E (0.38) KDM4EOGTUSP2MAPTRECQL
SCHEMBL10995851 0.60
SCHEMBL10995850 0.60
SCHEMBL16671202 0.60 KDM4E (0.38) KDM4EOGTUSP2MAPTRECQL
SCHEMBL625917 0.58
SCHEMBL11078676 0.57
SCHEMBL11078674 0.57
SCHEMBL123424 0.56
SCHEMBL11860484 0.56 KDM4E (0.38) KDM4EOGTUSP2MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0090297-A2 Process for preparing N,N'-disubstituted 5-acylimino-imidazolidine diones BAYER AG (DE) 1983-10-05 EP disclosed