SCHEMBL11220570

SCHEMBL11220570

C=CI.O=C1CC=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11192500 0.82
SCHEMBL52489 0.80
SCHEMBL11376825 0.80 TRIM24 (0.31)
Methane SCHEMBL29266080 0.77
Iodide SCHEMBL11339547 0.77
Methylamine SCHEMBL8994444 0.71
SCHEMBL1334117 0.67
Cyclopentanone SCHEMBL2797347 0.67 TRIM24 (0.62)
SCHEMBL489453 0.65
SCHEMBL11220569 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4338252-A BRONCHODILATORS, HYPOTENSIVE, ANTIULCER AMERICAN CYANAMID COMPANY (US) 1982-07-06 US disclosed
US-4328359-A 15-Deoxy-16-substituted-19-chloro-20-nor-prostane derivatives of the E and F series AMERICAN CYANAMID COMPANY (US) 1982-05-04 US disclosed
US-4322546-A HYPOTENSIVE AGENTS, ANTISECRETORY AGENTS, ANTIFERTILITY AGENTS, BRONCHODILATOR AGENTS AMERICAN CYANAMID COMPANY (US) 1982-03-30 US disclosed
US-4310700-A 1-Hydroxylmethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives AMERICAN CYANAMID COMPANY (US) 1982-01-12 US disclosed
US-4297516-A PROSTAGLANDINS AMERICAN CYANAMID COMPANY (US) 1981-10-27 US disclosed
US-4291174-A PROSTAGLANDINS AMERICAN CYANAMID COMPANY (US) 1981-09-22 US disclosed
US-4291175-A PROSTAGLANDINS USEFUL AS HYPOTENSIVE AGENTS, GASTRIC SECRETORY AND PLATELET AGGREGATION INHIBITORS, AND BRONCHODILATORS AMERICAN CYANAMID COMPANY (US) 1981-09-22 US disclosed
US-4289910-A PROSTAGLANDIN ANALOGS AMERICAN CYANAMID COMPANY (US) 1981-09-15 US disclosed
US-4288632-A HYPOTENSIVES, ANTISECRETORY, ANTICOAGULANTS, BRONCHODILATORS AMERICAN CYANAMID COMPANY (US) 1981-09-08 US disclosed
US-4288633-A PROSTAGLANDIN ANALOGS; ANTISECRETORY, HYPOTENSIVE, ANTICOAGULANT, BRONCHODILATING AMERICAN CYANAMID COMPANY (US) 1981-09-08 US disclosed
US-4267361-A HYPOTENSIVE, ANTIULCER, AND BRONCHODILATOR AGENTS AMERICAN CYANAMID COMPANY (US) 1981-05-12 US disclosed
US-4265904-A BRONCHODILATOR AGENTS AMERICAN CYANAMID COMPANY (US) 1981-05-05 US disclosed
US-4260805-A BRONCHODILATOR AGENTS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS AMERICAN CYANAMID COMPANY (US) 1981-04-07 US disclosed
US-4254275-A BRONCHODILATORS, ANTIULCER, HYPOTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1981-03-03 US disclosed
US-4254278-A BRONCHODILATORS, ANTIULCER, HYPOTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1981-03-03 US disclosed
US-4254036-A 1-Hydroxymethyl-1-oxo-prostane-derivatives of the E, A and F-series AMERICAN CYANAMID COMPANY (US) 1981-03-03 US disclosed
US-4250321-A BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS AMERICAN CYANAMID COMPANY (US) 1981-02-10 US disclosed
US-4250323-A BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS AMERICAN CYANAMID COMPANY (US) 1981-02-10 US disclosed
US-4235924-A BRONCHODILATION, PROSTAGLANDINS AMERICAN CYANAMID COMPANY (US) 1980-11-25 US disclosed
US-4233453-A HYPOTENSIVES, ANTISECRETORIES, BRONCHODILATORS, FERTILITY CONTROL AMERICAN CYANAMID COMPANY (US) 1980-11-11 US disclosed