Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.62 |
| ▸ | DRD3 | P35462 | 3/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.62 |
| ▸ | HRH1 | P35367 | 3/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.62 |
| ▸ | HRH2 | P25021 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568220 | 0.91 | KMT2A (0.73) | CYP2D6MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL7276991 | 0.91 | KMT2A (0.73) | CYP2D6MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL7283033 | 0.89 | CYP2D6 (0.65) | CYP2D6MEN1KMT2AOPRM1OPRD1 | |
| Water SCHEMBL7268828 | 0.88 | CYP2D6 (0.64) | CYP2D6MEN1KMT2AOPRM1OPRD1 | |
| Water SCHEMBL7290047 | 0.88 | CYP2D6 (0.64) | CYP2D6MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL29175113 | 0.85 | HRH1 (0.67) | CYP2D6OPRM1DRD3KCNH2HRH1 | |
| SCHEMBL29175114 | 0.85 | HRH1 (0.67) | CYP2D6OPRM1DRD3KCNH2HRH1 | |
| SCHEMBL1405261 | 0.83 | DRD3 (0.76) | CYP2D6MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL16757495 | 0.83 | KCNH2 (0.66) | CYP2D6MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL16769336 | 0.83 | KCNH2 (0.66) | CYP2D6MEN1KMT2AOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57031678-A | — | — | None | — | — | JP | disclosed |
| JP-S5731678-A | 1-(4-CHLOROBENZHYDRYL)-4-(2,3-BISHYDROXYPROPYL)- PIPERAZINE, MANUFACTURE AND MEDICINAL COMPOSITION AS EFFECTIVE COMPONENT THEREOF | SELVI & C SPA | 1982-02-20 | — | — | JP | disclosed |