Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.73 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
| ▸ | IGF1R | P08069 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276991 | 1.00 | KMT2A (0.73) | KMT2AMEN1OPRM1OPRD1ADRA2A | |
| SCHEMBL11220573 | 0.91 | CYP2D6 (0.65) | KMT2AMEN1OPRM1OPRD1ADRA2A | |
| SCHEMBL7266954 | 0.85 | KMT2A (0.71) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10992721 | 0.85 | MEN1 (1.00) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL7267603 | 0.84 | IGF1R (0.66) | KMT2AMEN1OPRM1OPRD1ADRA2A | |
| SCHEMBL9123119 | 0.83 | MEN1 (0.73) | KMT2AMEN1OPRM1OPRD1ADRA2A | |
| Hydrochloric Acid SCHEMBL10990138 | 0.83 | MEN1 (0.97) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL6161637 | 0.83 | KMT2A (0.68) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL11133461 | 0.81 | KMT2A (0.72) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL16109403 | 0.81 | OPRM1 (0.71) | KMT2AMEN1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4849423-A | Purine derivatives, medicaments containing them and methods of treating cardiac insufficiencies and irregularities with them. | SANDOZ LTD. (CH) | 1989-07-18 | — | — | US | disclosed |