Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 8/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.64 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293145 | 0.81 | PDE3B (0.57) | PDE3BPDE3AKDM1ADRD2HTR1A | |
| SCHEMBL6329420 | 0.80 | DRD4 (0.50) | PDE3BPDE3ADRD2HTR1AHTR2A | |
| SCHEMBL10923658 | 0.79 | PDE3B (0.55) | PDE3BPDE3AKDM1ADRD2DRD4 | |
| SCHEMBL24508418 | 0.79 | PDE3B (0.57) | PDE3BPDE3AKDM1ADRD2HTR1A | |
| SCHEMBL14816115 | 0.78 | SMN1; SMN2 (0.57) | PDE3BPDE3AP2RY12ALDH1A1MAPT | |
| SCHEMBL30871998 | 0.77 | DRD4 (0.59) | PDE3BPDE3ADRD2DRD4DRD3 | |
| SCHEMBL1494348 | 0.77 | DRD4 (0.59) | PDE3BPDE3ADRD2DRD4DRD3 | |
| SCHEMBL20424894 | 0.77 | DRD4 (0.52) | DRD2HTR1AHTR2ADRD4DRD3 | |
| SCHEMBL14815900 | 0.76 | PDE3B (0.50) | PDE3BPDE3AKDM1ADRD4DRD3 | |
| SCHEMBL24508429 | 0.74 | KDM1A (0.61) | PDE3BPDE3AKDM1ADRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57209281-A | — | — | None | — | — | JP | disclosed |
| JP-S57209281-A | BENZOXAZINE DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1982-12-22 | — | — | JP | disclosed |