Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1494348 | 1.00 | DRD4 (0.59) | DRD4DRD3DRD2POLBKDM4E | |
| SCHEMBL6301419 | 0.91 | DRD4 (0.58) | DRD4DRD3DRD2POLBKDM4E | |
| SCHEMBL705600 | 0.87 | MAPT (0.64) | DRD4DRD2POLBKDM4EALDH1A1 | |
| SCHEMBL6297491 | 0.84 | KIF11 (0.58) | DRD4DRD3DRD2POLBKDM4E | |
| SCHEMBL15964652 | 0.84 | PDE3B (0.50) | DRD4DRD3DRD2POLBKDM4E | |
| SCHEMBL5667155 | 0.82 | POLB (0.47) | DRD4DRD3DRD2POLBKDM4E | |
| SCHEMBL7474881 | 0.81 | MAPT (0.47) | DRD4DRD2POLBKDM4EALDH1A1 | |
| SCHEMBL6757684 | 0.80 | KIF11 (0.50) | DRD4DRD3DRD2PDE3BPDE3A | |
| SCHEMBL13932053 | 0.80 | MAPT (0.57) | DRD4DRD3DRD2POLBKDM4E | |
| SCHEMBL4271342 | 0.80 | MAPT (0.57) | DRD4DRD3DRD2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299464-A1 | BOTANICAL COMPOUNDS, METHODS, AND PROCEDURES FOR MEDICINAL TREATMENT RELATED TO IMMUNOINFLAMMATION, NEUROINFLAMMATION, DEPRESSION, MEMORY, FOCUS, AND NERVE DEGENERATION | NGUYEN MINH H (US) | 2024-09-12 | — | — | US | disclosed |
| WO-2024173722-A2 | BOTANICAL COMPOUNDS, METHODS, AND PROCEDURES FOR MEDICINAL TREATMENT RELATED TO IMMUNOINFLAMMATION, NEUROINFLAMMATION, DEPRESSION, MEMORY, FOCUS, AND NERVE DEGENERATION | NGUYEN MINH H (US) | 2024-08-22 | — | — | WO | disclosed |
| CN-117794534-A | Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof | 尤尼根公司 | 2024-03-29 | — | — | CN | disclosed |