Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650323 | 1.00 | TDP1 (0.42) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL11209290 | 1.00 | TDP1 (0.42) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL4650320 | 1.00 | TDP1 (0.42) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL11210335 | 1.00 | TDP1 (0.42) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL4651365 | 0.95 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL4650236 | 0.95 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL4650331 | 0.95 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL4652382 | 0.95 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL4650284 | 0.95 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL10510191 | 0.84 | TDP1 (0.43) | TDP1TSHRTRPV1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002588-B1 | PLEUROMUTILIN GLYCOSIDE DERIVATIVES, FORMULATIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1983-04-06 | — | — | EP | disclosed |
| EP-0002588-A1 | Pleuromutilin glycoside derivatives, formulations containing them and processes for their preparation | ELI LILLY AND COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
| US-4130709-A | BACTERICIDE | ELI LILLY AND COMPANY (US) | 1978-12-19 | — | — | US | disclosed |