Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651365 | 1.00 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL4650331 | 1.00 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL4652382 | 1.00 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL4650236 | 1.00 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL4650323 | 0.95 | TDP1 (0.42) | TDP1TSHRTRPV1 | |
| SCHEMBL11209290 | 0.95 | TDP1 (0.42) | TDP1TSHRTRPV1 | |
| SCHEMBL11210335 | 0.95 | TDP1 (0.42) | TDP1TSHRTRPV1 | |
| SCHEMBL11220951 | 0.95 | TDP1 (0.42) | TDP1TSHRTRPV1 | |
| SCHEMBL4650320 | 0.95 | TDP1 (0.42) | TDP1TSHRTRPV1 | |
| SCHEMBL17748350 | 0.84 | TDP1 (0.46) | TDP1TSHRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771181-B1 | PHOSPHOLE DERIVATIVES COMPLEXED WITH METALS, AND PHARMACEUTICAL USES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2008-09-10 | — | — | EP | claimed |
| US-4645756-A | ANTITUMOR, ANTICANCER AGENT | SMITH KLINE BECKMAN CORPORATION (US) | 1987-02-24 | — | — | US | claimed |
| EP-0189306-A2 | [alpha, omega-bis(diphenylphosphino)hydrocarbon]bis[(thiosugar)-gold]and bis[selenosugar)gold]derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1986-07-30 | — | — | EP | claimed |
| EP-0198696-B1 | PHOSPHINE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-04-11 | — | — | EP | disclosed |
| US-4902675-A | ANTITUMOR AGENTS | SMITHKLINE BECKMAN CORPORATION (US) | 1990-02-20 | — | — | US | disclosed |
| US-4698422-A | Triphos and tetraphos gold compounds and ligands | SMITHKLINE BECKMAN CORPORATION (US) | 1987-10-06 | — | — | US | disclosed |
| US-4645756-A | ANTITUMOR, ANTICANCER AGENT | SMITH KLINE BECKMAN CORPORATION (US) | 1987-02-24 | — | — | US | disclosed |
| EP-0189306-A2 | [alpha, omega-bis(diphenylphosphino)hydrocarbon]bis[(thiosugar)-gold]and bis[selenosugar)gold]derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1986-07-30 | — | — | EP | disclosed |