Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HBB | P68871 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221100 | 1.00 | KMT2A (0.51) | KMT2AMEN1TDP1MAPTMAPK1 | |
| SCHEMBL13350958 | 0.80 | MAPT (0.49) | KMT2AMEN1TDP1MAPTMAPK1 | |
| SCHEMBL13318800 | 0.73 | ALDH1A1 (0.40) | KMT2AMEN1TDP1MAPTMAPK1 | |
| SCHEMBL11204869 | 0.72 | — | — | |
| SCHEMBL3193895 | 0.71 | CCNT1 (0.37) | KMT2AMEN1TDP1MAPTMAPK1 | |
| SCHEMBL11545773 | 0.68 | MEN1 (0.59) | KMT2AMEN1TDP1MAPTMAPK1 | |
| SCHEMBL11545770 | 0.68 | MEN1 (0.59) | KMT2AMEN1TDP1MAPTMAPK1 | |
| SCHEMBL27834022 | 0.68 | MEN1 (1.00) | KMT2AMEN1TDP1MAPTMAPK1 | |
| SCHEMBL27328547 | 0.68 | MEN1 (0.63) | KMT2AMEN1TDP1MAPTMAPK1 | |
| SCHEMBL15274139 | 0.66 | MEN1 (1.00) | KMT2AMEN1TDP1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322212-A | AS COUPLERS WITH CONVENTIONAL DEVELOPERS IN AQUEOUS SOLUTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1982-03-30 | — | — | US | disclosed |