Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115310 | 0.84 | NOTUM (0.65) | NOTUMNR3C2ALDH1A1MAPTKDM4E | |
| SCHEMBL30763696 | 0.83 | NOTUM (0.63) | NOTUMKMT2AMEN1NR3C2ALDH1A1 | |
| SCHEMBL2878376 | 0.83 | NOTUM (0.63) | NOTUMKMT2AMEN1NR3C2ALDH1A1 | |
| SCHEMBL6886131 | 0.82 | KMT2A (0.49) | NOTUMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11216414 | 0.81 | KMT2A (0.48) | NOTUMKMT2AMEN1NR3C2ALDH1A1 | |
| SCHEMBL15018177 | 0.80 | NOTUM (0.72) | NOTUMKMT2ANR3C2ALDH1A1MAPT | |
| SCHEMBL27774897 | 0.79 | KMT2A (0.65) | NOTUMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28841086 | 0.77 | NOTUM (0.69) | NOTUMKMT2ANR3C2ALDH1A1MAPT | |
| SCHEMBL13500647 | 0.76 | ALDH1A1 (0.41) | NOTUMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL18054200 | 0.75 | NOTUM (0.49) | NOTUMKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57159765-A | — | — | None | — | — | JP | disclosed |
| JP-S57159765-A | 4-SUBSTITUTED-1-METHOXYCARBONYLINDOLE COMPOUND | NISSAN CHEM IND LTD | 1982-10-01 | — | — | JP | disclosed |