Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | HPGD | P15428 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | FHIT | P49789 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844533 | 0.87 | CYP3A4 (0.49) | ALDH1A1HPGDCYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL844171 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL5988684 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL11192938 | 0.77 | GRM6 (0.47) | ALDH1A1HPGDCYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL11355720 | 0.76 | CYP3A4 (0.47) | ALDH1A1HPGDCYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL29078846 | 0.75 | CYP3A4 (0.58) | ALDH1A1HPGDCYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL11215789 | 0.75 | CYP3A4 (0.58) | ALDH1A1HPGDCYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL27830604 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HPGDCYP3A4SMN1; SMN2MAPT | |
| SCHEMBL11199103 | 0.75 | ESR1 (0.48) | ALDH1A1CYP3A4SMN1; SMN2TDP1MAPT | |
| SCHEMBL7379340 | 0.73 | CYP3A4 (0.51) | ALDH1A1HPGDCYP3A4SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57200337-A | — | — | None | — | — | JP | disclosed |
| JP-S57200337-A | NOVEL 2-ACYLANILINE DERIVATIVE | ISHIKAWA MASAYUKI | 1982-12-08 | — | — | JP | disclosed |