Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12402241 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28050716 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27562418 | 0.94 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL12255537 | 0.94 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7760391 | 0.94 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL272304 | 0.92 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554427 | 0.91 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554406 | 0.91 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554404 | 0.91 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554423 | 0.91 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339527-A | BIS/ACRYLOYLOXYALKYL/HYDROCARBYLDICARBOXYLATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | claimed |
| US-4230790-A | COMPRISING A PHOTOINITIATOR, A POLYMERIC BINDER, AND AN ACRYLIC ESTER OF A DICARBOXYLIC ACID AND A GLYCOL ACRYLATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-28 | — | — | US | claimed |
| US-20090009061-A1 | Composition for Conductive Materials Comprising Crosslinkable Arylamine Compounds and Use Thereof in Electronic Devices and Electronic Equipment | SEIKO EPSON CORPORATION (JP) | 2009-01-08 | — | — | US | disclosed |
| US-4339527-A | BIS/ACRYLOYLOXYALKYL/HYDROCARBYLDICARBOXYLATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4297099-A | BY PENETRATION AND CROSSLINKING | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1981-10-27 | — | — | US | disclosed |
| US-4230790-A | COMPRISING A PHOTOINITIATOR, A POLYMERIC BINDER, AND AN ACRYLIC ESTER OF A DICARBOXYLIC ACID AND A GLYCOL ACRYLATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090009061-A1 | Composition for Conductive Materials Comprising Crosslinkable Arylamine Compounds and Use Thereof in Electronic Devices and Electronic Equipment | AHR, SLC43A1, SLC1A2 | TSHR 3348/4885POLB 3569/4885APEX1 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.