Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | GALR3 | O60755 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27764242 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19NPC1 | |
| Bromide SCHEMBL27702460 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19NPC1 | |
| Bromide SCHEMBL29690717 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19NPC1 | |
| Bromide SCHEMBL29078515 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19NPC1 | |
| Bromide SCHEMBL28352275 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19NPC1 | |
| Bromide SCHEMBL27658142 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19NPC1 | |
| Bromide SCHEMBL4449106 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19NPC1 | |
| Bromide SCHEMBL29078526 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19NPC1 | |
| Bromide SCHEMBL29690524 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2D6CYP2C19NPC1 | |
| SCHEMBL3817691 | 0.98 | PTGS1 (0.34) | ALDH1A1CYP1A2CYP2D6CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119909550-A | Preparation method and application of high-flux high-selectivity polyamide nanofiltration membrane | 沧州市天津工业大学研究院 | 2025-05-02 | — | — | CN | claimed |
| CN-119909550-A | Preparation method and application of high-flux high-selectivity polyamide nanofiltration membrane | 沧州市天津工业大学研究院 | 2025-05-02 | — | — | CN | disclosed |
| CN-111398605-B | Glycosylated hemoglobin measurement composition | 龟甲万株式会社 | 2024-04-05 | — | — | CN | disclosed |
| CN-117581338-A | Etching composition for semiconductor substrate for memory element and method for manufacturing semiconductor substrate for memory element using same | 三菱瓦斯化学株式会社 | 2024-02-20 | — | — | CN | disclosed |
| CN-117015849-A | Method for manufacturing semiconductor substrate for memory element | 三菱瓦斯化学株式会社 | 2023-11-07 | — | — | CN | disclosed |
| CN-116888249-A | Effervescent bactericidal composition | 雷克特和科尔曼(海外)家用卫生有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116806366-A | Composition for cleaning semiconductor substrate, and method for cleaning and method for manufacturing semiconductor substrate | 三菱瓦斯化学株式会社 | 2023-09-26 | — | — | CN | disclosed |
| CN-112521287-A | Nitrogen-containing amphiphilic organic ion manganese halide luminescent material and preparation method and application thereof | 华南理工大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-103254238-A | Novel heteroleptic iridium complexes | UNIVERSAL DISPLAY CORP | 2013-08-21 | — | — | CN | disclosed |
| CN-101175792-B | Curable composition | MITSUBISHI GAS CHEMICAL CO | 2011-01-26 | — | — | CN | disclosed |
| CN-101175792-A | curable composition | MITSUBISHI GAS CHEMICAL CO (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-1102647-C | Improved composition containing organic compounds | RECKITT & COLMAN INC (US) | 2003-03-05 | — | — | CN | disclosed |
| CN-1204361-A | Improved composition containing organic compounds | RECKITT & COLMAN INC (US) | 1999-01-06 | — | — | CN | disclosed |
| US-4329185-A | Method for the preparation of a biologically active polyamide net | DSO "PHARMACHIM" (BG) | 1982-05-11 | — | — | US | disclosed |