Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220053 | 0.89 | ACE (0.42) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL11321332 | 0.88 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL11326224 | 0.78 | ALDH1A1 (0.41) | DPP4ALDH1A1ACE | |
| SCHEMBL11310145 | 0.77 | NPSR1 (0.45) | NPSR1ALDH1A1 | |
| SCHEMBL11321340 | 0.74 | ALDH1A1 (0.50) | NPSR1DPP4ALDH1A1L3MBTL1 | |
| SCHEMBL11155524 | 0.73 | HRH3 (0.55) | PREPFAPACE | |
| SCHEMBL11220472 | 0.72 | NPSR1 (0.47) | ITGB3ITGB1ITGAVITGA5NPSR1 | |
| SCHEMBL5741063 | 0.71 | HPGD (0.63) | ALDH1A1ACE | |
| SCHEMBL5741058 | 0.71 | HPGD (0.63) | ALDH1A1ACE | |
| SCHEMBL22209433 | 0.71 | PREP (0.55) | DPP4PREPFAPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003056-B1 | N-SUBSTITUTED OMEGA-AMINOALKANOYL-OMEGA-AMINOALKANECARBOXYLIC ACIDS, THEIR APPLICATION AND PROCESS FOR THEIR PREPARATION, AND MEDICINES CONTAINING THESE COMPOUNDS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-08-18 | — | — | EP | disclosed |
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |
| EP-0003056-A1 | N-substituted omega-aminoalkanoyl-omega-aminoalkanecarboxylic acids, their application and process for their preparation, and medicines containing these compounds | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1979-07-25 | — | — | EP | disclosed |