SCHEMBL1122230

SCHEMBL1122230

COC1=CC=CC(N)(OC)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771440 0.79
SCHEMBL27940357 0.78
SCHEMBL28711085 0.75
SCHEMBL12282146 0.74
SCHEMBL16010389 0.73
SCHEMBL3419721 0.73
SCHEMBL6322210 0.73
SCHEMBL1735727 0.73
SCHEMBL29575061 0.73
SCHEMBL30665884 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390656-B Compound and preparation method and application thereof 中国医学科学院医药生物技术研究所 2025-04-08 CN claimed
CN-119390656-A Compound and preparation method and application thereof 中国医学科学院医药生物技术研究所 2025-02-07 CN claimed
CN-103266166-B Glucose detecting reagent NINGBO MEDICAL SYSTEM BIOTECHNOLOGY CO LTD 2015-04-29 CN claimed
CN-103266166-A Glucose detecting reagent NINGBO MEDICAL BIOLOG TECHNOLOGY CO LTD 2013-08-28 CN claimed
CN-1696127-A Analogue of thalidomide and preparation method CHANGCHUN APPLIED CHEMISTRY (CN) 2005-11-16 CN claimed
CN-119390656-B Compound and preparation method and application thereof 中国医学科学院医药生物技术研究所 2025-04-08 CN disclosed
CN-119390656-A Compound and preparation method and application thereof 中国医学科学院医药生物技术研究所 2025-02-07 CN disclosed
CN-103266166-B Glucose detecting reagent NINGBO MEDICAL SYSTEM BIOTECHNOLOGY CO LTD 2015-04-29 CN disclosed
CN-103266166-A Glucose detecting reagent NINGBO MEDICAL BIOLOG TECHNOLOGY CO LTD 2013-08-28 CN disclosed
EP-1831184-B1 PYRAZINES AND PYRIDINES AND DERIVATIVES THEREOF AS THERAPEUTIC COMPOUNDS WELLCOME TRUST LTD (GB) 2011-02-09 EP disclosed
US-7737152-B2 6-carboaryl-oxy-pyrazin-2-yl-carboaryl-amines and compositions comprising said compounds THE WELLCOME TRUST LIMITED (GB) 2010-06-15 US disclosed
US-20080015191-A1 Pyrazines and Pyridines and Derivatives Thereof as Therapeutic Compounds THE WELLCOME TRUST LIMITED (UK) 2008-01-17 US disclosed
EP-1831184-A2 PYRAZINES AND PYRIDINES AND DERIVATIVES THEREOF AS THERAPEUTIC COMPOUNDS The Wellcome Trust Limited (GB) 2007-09-12 EP disclosed
WO-2006067466-A2 PYRAZINES AND PYRIDINES AND DERIVATIVES THEREOF AS THERAPEUTIC COMPOUNDS THE WELLCOME TRUST LIMITED (GB) 2006-06-29 WO disclosed
CN-1696127-A Analogue of thalidomide and preparation method CHANGCHUN APPLIED CHEMISTRY (CN) 2005-11-16 CN disclosed
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US disclosed
US-6162931-A Fluorinated xanthene derivatives MOLECULAR PROBES, INC. (US) 2000-12-19 US disclosed