SCHEMBL8771440

SCHEMBL8771440

COC1(N)C=CC=C(N)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL8517991 0.89
SCHEMBL1122230 0.79
SCHEMBL29236046 0.77
SCHEMBL28300405 0.75
SCHEMBL30721508 0.73
SCHEMBL28400917 0.72 TDP1 (0.34)
SCHEMBL9586241 0.71
SCHEMBL28703048 0.70
SCHEMBL30163541 0.69
SCHEMBL27896020 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4046503-A DEVELOPER-COUPLER HAIR DYES BASED ON ALKOXY-TRIAMINO-PYRIMIDINES HENKEL & CIE GMBH (DT) 1977-09-06 US claimed
US-4043750-A OXIDATION HENKEL & CIE GMBH (DT) 1977-08-23 US claimed
EP-0658099-B1 ANTI-FREE-RADICAL TOPICAL COMPOSITION BASED ON A SUPEROXIDE DISMUTASE AND A PHOSPHONIC DERIVATIVE OREAL (FR) 1997-08-13 EP disclosed
EP-0658099-A1 ANTI-FREE-RADICAL TOPICAL COMPOSITION BASED ON A SUPEROXIDE DISMUTASE AND A PHOSPHONIC DERIVATIVE. OREAL (FR) 1995-06-21 EP disclosed
US-5352438-A Used to protect skin from aging and radiation exposure L'OREAL (FR) 1994-10-04 US disclosed
WO-1992019224-A2 ANTI-FREE-RADICAL TOPICAL COMPOSITION BASED ON A SUPEROXIDE DISMUTASE AND A PHOSPHONIC DERIVATIVE L'OREAL (FR) 1992-11-12 WO disclosed
US-4566876-A COLORFAST SHADES OF BLUE AND BROWN CLAIROL INCORPORATED (US) 1986-01-28 US disclosed
US-4417896-A NITRO-,AMINO-,PHENOXYALKANOLS SOCIETE ANONYME DITE: L'OREAL (FR) 1983-11-29 US disclosed
US-4337061-A NITRO DYES IN AQUEOUS SOLUTION SOCIETE ANONYME DITE: L'OREAL (FR) 1982-06-29 US disclosed