SCHEMBL11222640

SCHEMBL11222640

O=C(Cl)C1C=CC(C(=O)Cl)CC1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19091678 0.85
SCHEMBL17056228 0.80
SCHEMBL17056244 0.80
SCHEMBL30420169 0.78
SCHEMBL8393475 0.75
SCHEMBL638769 0.71 POLB (0.46) POLBAPEX1TDP1
SCHEMBL27454615 0.69 POLB (0.36) POLBTDP1
SCHEMBL27429384 0.66
SCHEMBL2266700 0.65 GABRR1 (0.35)
SCHEMBL7271372 0.65 GABRR1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160075826-A1 PROCESS FOR MANUFACTURING POLYAMIDE AKRON POLYMER SYSTEMS, INC. (US) 2016-03-17 US claimed
US-20160039974-A1 PROCESS FOR MANUFACTURING POLYAMIDE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2016-02-11 US claimed
US-20160032052-A1 PROCESS FOR MANUFACTURING POLYAMIDE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2016-02-04 US claimed
US-20160075826-A1 PROCESS FOR MANUFACTURING POLYAMIDE AKRON POLYMER SYSTEMS, INC. (US) 2016-03-17 US disclosed
US-20160039974-A1 PROCESS FOR MANUFACTURING POLYAMIDE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2016-02-11 US disclosed
US-20160032052-A1 PROCESS FOR MANUFACTURING POLYAMIDE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2016-02-04 US disclosed
US-4337154-A FORMED FROM A POLYALKYLENIMINE AND A NITROGEN-HETEROCYCLIC SECONDARY AMINE COMPOUND NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1982-06-29 US disclosed