Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.84 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.52 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL11232097 | 1.00 | GPR84 (0.84) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28089828 | 0.94 | GPR84 (0.81) | GPR84FFAR1MAPTLCKPPARD | |
| Monoethanolamine SCHEMBL7203172 | 0.92 | GPR84 (0.78) | GPR84FFAR1MAPTLCKPPARD | |
| Monoethanolamine SCHEMBL11778579 | 0.92 | GPR84 (0.78) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL525700 | 0.92 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL4757199 | 0.92 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL22842 | 0.92 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2933185 | 0.92 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2709599 | 0.92 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL525377 | 0.92 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953218-A | Pigment dispersion | PMS CONSOLIDATED (US) | 1976-04-27 | — | — | US | claimed |
| CN-212463677-U | Multilayer wiring board and electronic device | 株式会社村田制作所 | 2021-02-02 | — | — | CN | disclosed |
| CN-211321678-U | Multilayer wiring board | 株式会社村田制作所 | 2020-08-21 | — | — | CN | disclosed |
| CN-107406664-A | Thermoplastic resin composition, lid material and easily openable container | 安姆希比创新咨询有限公司 | 2017-11-28 | — | — | CN | disclosed |
| US-4309374-A | ENCAPSULATING PIGMENT PARTICLE IN FATTY AMIDE | PLASTIC MOLDERS SUPPLY CO., INC. (US) | 1982-01-05 | — | — | US | disclosed |
| US-3978036-A | MOLTEN FATTY ACID AMIDE | PMS CONSOLIDATED (US) | 1976-08-31 | — | — | US | disclosed |
| US-3953218-A | Pigment dispersion | PMS CONSOLIDATED (US) | 1976-04-27 | — | — | US | disclosed |
| US-3936403-A | Synthetic resin composition | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-02-03 | — | — | US | disclosed |