Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138 | 0.78 | GABRP (0.49) | KDM4ELMNAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL149486 | 0.78 | PIK3CD (0.49) | KDM4EALDH1A1HPGDHTTMEN1 | |
| SCHEMBL8473 | 0.78 | PIK3CD (0.49) | KDM4EALDH1A1HPGDHTTMEN1 | |
| SCHEMBL1781414 | 0.77 | GABRP (0.46) | KDM4EALDH1A1HPGDHTTMEN1 | |
| SCHEMBL8656 | 0.76 | GABRP (0.49) | KMT2ASMN1; SMN2MAPTL3MBTL1GABRP | |
| SCHEMBL8459 | 0.75 | GABRP (0.51) | KDM4EMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL11634 | 0.75 | GABRP (0.42) | KDM4EALDH1A1HPGDHTTMEN1 | |
| SCHEMBL27899985 | 0.75 | GABRP (0.42) | KDM4EALDH1A1HPGDHTTMEN1 | |
| SCHEMBL11222 | 0.74 | GABRP (0.40) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL8257 | 0.74 | GABRP (0.52) | KDM4ELMNAKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496567-A2 | NOVEL BENZOPYRAN KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011055215-A2 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-05-12 | — | — | WO | disclosed |