Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087140 | 0.82 | IAPP (0.41) | ODC1SMN1; SMN2HIF1ACA1CA2 | |
| SCHEMBL6720237 | 0.81 | AKR1B1 (0.47) | ODC1SMN1; SMN2HIF1ACA12CA2 | |
| SCHEMBL25581435 | 0.78 | ODC1 (0.43) | ODC1SMN1; SMN2HIF1AKDM4ECASP6 | |
| SCHEMBL2212930 | 0.77 | SMN1; SMN2 (0.60) | ODC1SMN1; SMN2HIF1ABLMCYP1A2 | |
| SCHEMBL2896017 | 0.76 | GRM2 (0.45) | SMN1; SMN2HIF1AKDM4ECASP6BLM | |
| SCHEMBL4245719 | 0.74 | BLM (0.59) | ODC1SMN1; SMN2HIF1ACA2KDM4E | |
| SCHEMBL4245716 | 0.74 | BLM (0.59) | ODC1SMN1; SMN2HIF1ACA2KDM4E | |
| SCHEMBL22033172 | 0.74 | BLM (0.59) | ODC1SMN1; SMN2HIF1ACA2KDM4E | |
| SCHEMBL10780736 | 0.73 | KDM4E (0.62) | SMN1; SMN2HIF1ACA1CA2KDM4E | |
| SCHEMBL6724640 | 0.73 | KDM4E (0.62) | SMN1; SMN2HIF1ACA1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342780-A | 2-AMINO-2-FLUOROMETHYL-3-(SUBSTITUTED) PHENYL PROPIONIC ACIDS AND DERIVATIVES COADMINISTERED WITH DOPAMINE | MERRELL-TORAUDE ET CIE (FR) | 1982-08-03 | — | — | US | claimed |
| US-4342780-A | 2-AMINO-2-FLUOROMETHYL-3-(SUBSTITUTED) PHENYL PROPIONIC ACIDS AND DERIVATIVES COADMINISTERED WITH DOPAMINE | MERRELL-TORAUDE ET CIE (FR) | 1982-08-03 | — | — | US | disclosed |