Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2715722 | 0.79 | ACE (0.56) | ACEITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL2805870 | 0.79 | ACE (0.56) | ACEITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL2712732 | 0.79 | ACE (0.56) | ACEITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL12764284 | 0.76 | GSK3B (0.32) | ACEGSK3B | |
| SCHEMBL2377674 | 0.76 | ACE (0.41) | ACE | |
| SCHEMBL30317311 | 0.76 | ACE (0.57) | ACEITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL8213582 | 0.76 | ACE (0.53) | ACEITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL6899829 | 0.76 | ACE (0.57) | ACEITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL6899827 | 0.76 | ACE (0.57) | ACEITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL13285260 | 0.75 | ACE (0.40) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57054167-A | — | — | None | — | — | JP | disclosed |
| JP-S5754167-A | PYROGLUTAMIC ACID DERIVATIVE AND ITS PREPARATION | ONO PHARMACEUT CO LTD | 1982-03-31 | — | — | JP | disclosed |