Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899827 | 1.00 | ACE (0.57) | ACEATMITGB1ITGA5MAPK1 | |
| SCHEMBL6899829 | 1.00 | ACE (0.57) | ACEATMITGB1ITGA5MAPK1 | |
| SCHEMBL2133052 | 0.86 | ACE (0.42) | ACEMAPK1POLBP2RX7CREBBP | |
| SCHEMBL7270652 | 0.85 | ACE (0.54) | ACEATMITGB1ITGA5ITGB3 | |
| SCHEMBL2712732 | 0.83 | ACE (0.56) | ACEITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL2715722 | 0.83 | ACE (0.56) | ACEITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL2805870 | 0.83 | ACE (0.56) | ACEITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL3062472 | 0.82 | ACE (0.41) | ACEMAPK1POLBP2RX7 | |
| SCHEMBL3062470 | 0.82 | ACE (0.41) | ACEMAPK1POLBP2RX7 | |
| SCHEMBL10668874 | 0.82 | ACE (0.51) | ACEATMITGB1ITGA5ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11629171-B2 | Beta-hairpin peptidomimetics | SPEXIS AG (CH) | 2023-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11629171-B2 | Beta-hairpin peptidomimetics | POLL, POLQ, HBZ | ACE 291/4885ATM 2210/4885ITGB1 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.