⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293708 | 0.75 | — | — | |
| SCHEMBL65952 | 0.75 | — | — | |
| SCHEMBL8208273 | 0.72 | HMBS (0.92) | — | |
| SCHEMBL6561706 | 0.72 | — | — | |
| SCHEMBL8619374 | 0.72 | — | — | |
| SCHEMBL12125855 | 0.67 | — | — | |
| SCHEMBL10054604 | 0.65 | HMBS (0.62) | — | |
| SCHEMBL1104622 | 0.65 | HMBS (0.62) | — | |
| SCHEMBL5272526 | 0.64 | GCGR (0.55) | — | |
| SCHEMBL10138656 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739331-B | A kind of synthetic method of 2-vhloro-5-chloromethylpyridine | 九江善水科技股份有限公司 | 2018-07-31 | — | — | CN | claimed |
| CN-107739331-A | A kind of synthetic method of the PMC of 2 chlorine 5 | 九江善水科技股份有限公司 | 2018-02-27 | — | — | CN | claimed |
| CN-109153642-B | Indole and azaindole halogenated allylamine derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114040915-A | Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors | 里伯赛恩斯有限责任公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-109476663-B | Pyrazolopyridine derivatives for the treatment of cancer | 基因泰克公司 | 2021-11-09 | — | — | CN | disclosed |
| EP-3590942-B1 | HEPATITIS B VIRUS SURFACE ANTIGEN INHIBITOR | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2021-06-09 | — | — | EP | disclosed |
| CN-109071533-B | Halogenated allylamine indole and azaindole derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2021-05-25 | — | — | CN | disclosed |
| EP-3611165-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |
| CN-110431134-A | Pyridine compounds as allosteric SHP2 inhibitors | REVOLUTION MEDICINES INC | 2019-11-08 | — | — | CN | disclosed |
| CN-110325535-A | Piperidine-, morpholine-or piperazine-substituted [1,2,4] -triazolo [1,5-a ] -pyrimidinyl derivatives as OGA inhibitors | 詹森药业有限公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-105308048-B | Substituted 2-azabicyclic compounds and their use as orexin receptor modulators | 詹森药业有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-103848838-A | c-Met-VEGFR-2 double antagonist, preparation method and medical use thereof | UNIV CHINA PHARMA | 2014-06-11 | — | — | CN | disclosed |
| CN-102464667-B | Five-membered heterocycle pyrimidine compounds, preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2014-06-04 | — | — | CN | disclosed |
| WO-2013127780-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-09-06 | — | — | WO | disclosed |
| US-20120202794-A1 | COMPOUNDS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202794-A1 | COMPOUNDS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2011050160-A1 | PHARMACEUTICALS, COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2011-04-28 | — | — | WO | disclosed |
| US-20100028299-A1 | Methods and compositions of treating a flaviviridae family viral infection | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-02-04 | — | — | US | disclosed |
| CN-100577663-C | Fused heterocyclic kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2010-01-06 | — | — | CN | disclosed |
| EP-0072013-A1 | Pyrrole compounds as anti-inflammatory and analgesic agents | MERCK & CO. INC. (US) | 1983-02-16 | — | — | EP | disclosed |